The 1918 influenza virus was a bird flu that jumped directly to humans, two teams of scientists announced today.

The work also reveals that the 1918 virus is very different from ordinary human flu viruses. It infects cells deep in the lungs of mice, and infects lung cells, like the cells lining air sacs, that normally would be impervious to flu. And while other human flu viruses do not kill mice, this one, like today’s bird flus, does.

But Dr. Jeffery Taubenberger, chief of molecular pathology department at the Armed Forces Institute of Pathology, notes that the bird flus have not yet spread from human to human. He hopes the 1918 virus will reveal what genetic changes can allow that to happen, helping scientists prevent a new pandemic before it starts.

Read (New York Times)